510 Sterilizable-in-Place (SIP) Benchtop or Mobile Bioreactor
& 40 Liters Total Volume)
Video: Critical Considerations for Selecting
or Bioreactor Vendor
For the Ultimate in Convenience, System Flexibility and
Brunswick Scientific's CelliGen 510 bioreactors are cGMP-compliant, benchtop or
mobile, sterilizable-in-place systems for pilot through production applications.
Ideal for growth of any mammalian, insect or plant cell line, the bioreactor is
modular in design to enable system upgrades at any time, pre- or post-delivery,
to meet changes in your process needs. (For microbial fermentation, see our.)
The Modular Bioreactor Design Provides
Easily add or remove system
components at any time, pre- or post-delivery to accomodate changes in your
- Numerous ports in the vessel headplate and sidewall provide
flexibility to position probes, spray balls, addition valves, pressure
transducer and more, wherever needed.
- Multiple gas flow options let you optimize control, based on your
process needs. Up to 5 Thermal Mass Flow Controllers can be employed, four when
using a gas overlay, or choose a Rotameter.
- Capable of batch, fed-batch and continuous (perfusion) modes.
- Multiple impeller options provide flexibility to achieve high
yields from virtually any mammalian, insect or plant cell lines.
- Optional SCADA software, validation packages, sprayballs for
vessel clean-in-place, redundant pH/DO probes, resterilizable sample and
addition valves, and more, are available to customize the bioreactor system for
your lab or production-floor requirements.
Controller Optimizes Results.
Simultaneously regulate up to 32 process loops using our
sophisticated RPC Reactor Process Controller.
- Front-accessed, analog inputs and outputs allow you to integrate
up to 14 sensors, analyzers, flow controllers or other external devices, for
optimized system control.
- Security, built into the bioreactor's control system, offers two
user groups unique user-defined passwords and auto log-out.
- Touchscreen control screens are exceptionally easy to navigate,
to simplify bioreactor setup, calibration, sterilization and monitoring.
(Synoptic screen shown.)
- Trend eight process parameters simultaneously. Store up to ten
batch recipes. Program & monitor sterilization cycles, gas flow, PI values,
same controller is used in our benchtop CelliGen 310 & 510 bioreactors and
BioFlo 310 & 415 fermentors, facilitating scale-up and scale-down.
- Now available with Allen Bradley
CompactLogix Programmable Automation Controller for those who prefer the
flexibility and robustness of an industrial grade PLC. This option enables
complete machine control (recipes, valves, process loops) to optimize your
process. The bioprocess software program is nearly identical to the program
utilized by the NBS¡¯ larger-scale BioFlo and CelliGen Pro series facilitating
process scale-up and protocol development from 19.5L to 3000L, while eliminating
the need to train operators on multiple control systems.
Production-Scale Bioreactor System That Fits on the Bench!
At just 45.5" wide x 34.0¡± deep (116 x 86 cm), the compact
CelliGen 510 bioreactor fits on any lab bench. Or, move and operate it on our
sturdy, optional, stainless-steel mobile skid.
built-in load cell precisely measures vessel contents, enabling integrated
control of pumps for automatic addition of fresh media, pH, DO, or foam control
agents, or harvesting. Measurements are displayed on the RPC interface for easy
- Sterile vessel connections, flush with the vessel¡¯s interior,
virtually eliminate deadlegs, minimizing contamination risk and simplifying
CelliGen 510 Bioreactors¡¦ designed for rapid delivery and
easy field customization, should your requirements change. Compact, versatile,
and exceptionally capable. NBS quality at a very competitive